753B-parameter open-weight scientific model for chemistry, materials science and life sciences
huggingface.co/deep-principle/Hydrogen-1.0
Hydrogen-1.0 is Deep Principle's open-weight scientific model, released under the MIT licence on 2 November 2026. It was post-trained from GLM-5.3 on domain data from chemistry, materials science and life sciences, plus laboratory notebook records and discovery trajectories from Deep Principle's labs, to help with experiment planning, protocol design, simulation workflows and results analysis. Weights are on Hugging Face and ModelScope, with API access via NeuroSpark and use inside the Mira AI scientist.