Typewriter TPRT Platform
Non-viral, RNA-delivered platform for site-specific whole-gene insertion
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About
Typewriter’s TPRT (target-primed reverse transcription) platform uses lipid nanoparticle–delivered RNA to insert whole therapeutic genes at a specific natural safe-harbor locus, without viral vectors or double-strand breaks. The company describes the approach as precise, durable as cells divide, and designed to support re-dosable genetic medicines, with initial applications in in vivo CAR-T and hereditary liver disease programs.
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- typewritertx.com
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