Oral gamma-secretase modulator in Phase 1 for early Alzheimer's intervention
actapharmaceuticals.com/gsm-779690t
GSM-779690T is Acta Pharmaceuticals' lead investigational oral gamma-secretase modulator designed to reduce longer amyloid-beta forms such as Aβ42 while increasing shorter forms including Aβ37 and Aβ38. It is in a Phase 1 study in healthy adult participants (ClinicalTrials.gov NCT07690228), building on research from Massachusetts General Hospital, Harvard Medical School and UC San Diego collaborators.
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