Aptadir DiR Platform

Gene-selective RNA inhibitors of DNMT1 for demethylating medicines

aptadir.com

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About

Aptadir’s public platform centers on DNMTs Interacting RNAs (DiRs): modified RNA oligonucleotides that inhibit DNA methyltransferase 1 globally (aptaDiR) or at a locus (captaDiR) to reactivate silenced genes. The company is advancing candidates for genetic disorders and cancers based on this approach, as described on aptadir.com and in its September 2026 seed announcement.

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Gene-selective demethylation therapeuticsFragile X and oncology pipeline research

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