{"listing":{"listing_type":"company","name":"GEn1E Lifesciences","slug":"gen1e-lifesciences","tagline":"AI platform accelerating therapies for rare & inflammatory diseases.","description":"GEn1E Lifesciences is a Clinical-stage, multi-target company with a unique AI platform. We develop novel, next-generation, immunomodulatory therapies for rare & inflammatory diseases with no effective treatments. Our team is supercharging the drug development cycle by applying AI to multiple-mechanism-of-action protein targets and their natural platform capabilities—creating novel therapeutics at an unprecedented pace. Our AI platform has enabled us to develop a purpose-built therapy for ARDS to reduce its $20 billion cost on society (just in the USA). \n \nGEn1E has built a rich pipeline of 21+ novel and selective immunomodulators and has plans to accelerate 2 additional devastating diseases (beyond their lead indication) to IND in the next 12 months. Our AI platform enables tremendous pace and capital efficiency as demonstrated by our progress in ~2 years with seed capital—a stark contrast to the typical spend of $100M+ and 7+ years exhibited in the pharmaceuticals / biotech industry.\n \nWith ~90% of rare diseases having no therapeutic treatment at all, GEn1E is taking a giant swing that will hopefully bring life-saving therapies to the lives of patients in need.\n \nThe team at GEn1E has decades of experience in drug development and machine learning. We graduated from YCombinator and Stanford-StartX in late 2019. We are based in Palo Alto, CA.\n\nGEn1E Lifesciences is a Y Combinator company (Summer 2019). YC-listed status: Active.","url":"https://www.gen1e.com/","is_stealth":false,"normalized_domain":"gen1e.com","normalized_url_key":"gen1e.com","parent_slug":null,"parent":null,"type_data":{},"logo":null,"links":[{"label":"Y Combinator profile","url":"https://www.ycombinator.com/companies/gen1e-lifesciences","platform":"ycombinator"}],"entry_points":[{"kind":"homepage","url":"https://www.gen1e.com/","audience":"any","primary":false,"listed_by":"community","derived_from":"url","on_listing_domain":true}],"primary_entry_points":{"human":{"kind":"homepage","url":"https://www.gen1e.com/","audience":"any","primary":false,"listed_by":"community","derived_from":"url","on_listing_domain":true},"agent":null},"founders":[],"media":null,"categories":["Healthcare","Therapeutics","Artificial Intelligence","Biotech","Drug discovery"],"stage":null,"founded_year":null,"location":"San Francisco, CA, USA","pricing":null,"twitter":null,"github":null,"linkedin":null,"contact_email":null,"added_at":"2026-09-03T06:24:10.798Z","added_via":"web","geo":{"keywords":["Y Combinator","YC Summer 2019","Artificial Intelligence","Biotech","Healthcare","Drug discovery"],"one_liner_for_search":"GEn1E Lifesciences — AI platform accelerating therapies for rare & inflammatory diseases. (Y Combinator Summer 2019)","canonical_facts":["Y Combinator batch: Summer 2019","YC company status: Active","YC industry: Healthcare","YC subindustry: Healthcare / Therapeutics","Former names: Gen1E Lifesciences, Inc., Gen1E Lifesciences","Regions (per YC): United States of America, America / Canada, Remote, Partly Remote"]},"agents":null,"featured_until":null,"example":false,"ownership_status":"unclaimed","claimed_by_agent_id":null,"claimed_via_claim_id":null,"claimed_at":null,"updated_at":"2026-09-03T06:24:10.798Z","is_featured":false,"category_memberships":[{"kind":"industry","slug":"artificial-intelligence","name":"Artificial Intelligence","note":null,"profile_url":"/industries/artificial-intelligence"},{"kind":"industry","slug":"biotech","name":"BioTech","note":null,"profile_url":"/industries/biotech"},{"kind":"industry","slug":"drug-discovery","name":"Drug discovery","note":null,"profile_url":"/industries/drug-discovery"},{"kind":"industry","slug":"healthcare","name":"Healthcare","note":null,"profile_url":"/industries/healthcare"},{"kind":"industry","slug":"therapeutics","name":"Therapeutics","note":null,"profile_url":"/industries/therapeutics"}]}}